Vitrification

Cryotop®

Not just the device with the best proven results on the market, also the one with the best user experience.

Developed and manufactured in Japan, the Cryotop® allows to optimize your routine and results to the maximum.

Cryotop® allows you to achieve the best clinical results. Its unparalleled survival rates for oocytes and embryos, at every stage of development, have contributed to bringing hundreds of thousands of healthy babies into the world since its creation.

Cryotop® is a vitrification device consisting of a fine strip of transparent film attached to a plastic handle resistant to liquid nitrogen.

Its design allows the loading of specimens for vitrification with a minimum volume (0.1 µl), providing the best Cooling and Warming Rates on the market (-23,000ºC/minute and 42,000ºC/minute respectively) which, in turn, lead to the best survival rates.

Cryotop® is a vitrification device consisting of a fine strip of transparent film attached to a plastic handle resistant to liquid nitrogen.

Its design allows the loading of specimens for vitrification with a minimum volume (0.1 µl), providing the best Cooling and Warming Rates on the market (-23,000ºC/minute and 42,000ºC/minute respectively) which, in turn, lead to the best survival rates.

The revolutionary device by Kitazato is applied in more than 2,500,000 clinical cases for cryopreservation of oocytes and embryos annually, obtaining excellent results in over 115 countries and 3,000 assisted reproduction centers.

Key Features

  • Wider sheet for an easy loading of the specimens on the straw
  • Thin strip to allow high temperature exposure to specimens during vitrification and thawing
  • Diamond tip for an easy insertion into the cover straw
  • Identification marks to define the side where specimens should be loaded for quick location of the cryopreserved samples during thawing
  • Allows up to 4 specimens to be loaded per device

Highest Cooling and Warming Rates on the Market

Cooling and warming rates are essential parameters for the success of vitrification and thawing processes. These parameters, especially the warming ones, have a huge impact in specimens survival rates.

The Cryotop® vitrification device ensures a very high cooling and warming rates resulting into better survival and live birth rates.

This is achieved thanks to the design of the Cryotop®, with its characteristic thin strip, the use of small volumes surrounding the specimen, and the design of the vitrification and thawing protocols that allow excellent heat exchanges between the specimen and the LN2/Warming Media.

Highest Cooling and Warming Rates on the Market

Cooling and warming rates are essential parameters for the success of vitrification and thawing processes. These parameters, especially the warming ones, have a huge impact in specimens survival rates.

The Cryotop® vitrification device ensures a very high cooling and warming rates resulting into better survival and live birth rates.

This is achieved thanks to the design of the Cryotop®, with its characteristic thin strip, the use of small volumes surrounding the specimen, and the design of the vitrification and thawing protocols that allow excellent heat exchanges between the specimen and the LN2/Warming Media.

Large storage capacity

Optimizing space in the nitrogen tanks and choosing the most appropriate vitrification device, without compromising the viability of the samples, is one of the major challenges for clinics.

Cryotop® maximizes storage capacity and allows loading up to 4 oocytes without affecting the survival or reproductive potential of any of them.

Allowing multiple vitrifications per device, in addition to the small size of the Cryotop®, has made it the most versatile and widely used vitrification device in the world.

How to perform a succesfull vitrification

Embryo Vitrification and Thawing Protocol

Cryotop® US

Cryotop® US is a vitrification device exclusive for the U.S. market. Its design incorporates all of the benefits of the original Cryotop® with an external cover that hermetically seals the Cryotop® US tip with weight, to prevent floating in liquid nitrogen.

The Cryotop® Scoop, a single piece mold with a slightly thicker tip and rounded “shovel” design, is also available in the US market.

Cryotop® Closed System

Cryotop® SC and Cryotop® CL allow the device to be sealed within an outer straw. The sealed protocol ensures success during vitrification guaranteeing, at the same time, that the specimens and liquid nitrogen do not come into direct contact.

Cryotop® SC and Cryotop® CL are available in selected countries.

Order Number Code Color Specifications Quantity
81111 Cryotop® (G) Green Open 10/pack
81112 Cryotop® (R) Red Open 10/pack
81113 Cryotop® (W) White Open 10/pack
81114 Cryotop® (B) Blue Open 10/pack
81115 Cryotop® (Y) Yellow Open 10/pack

Order Number Code Color Specifications Quantity
81121 Cryotop® SC (G) Green Closed 10/pack
81122 Cryotop® SC (R) Red Closed 10/pack
81123 Cryotop® SC (W) White Closed 10/pack
81124 Cryotop® SC (B) Blue Closed 10/pack
81125 Cryotop® SC (Y) Yellow Closed 10/pack

Order Number Code Color Specifications Quantity
81171 Cryotop®US (G) Green Closed, Flat Sheet 10/pack
81172 Cryotop®US (R) Red Closed, Flat Sheet 10/pack
81173 Cryotop®US (W) White Closed, Flat Sheet 10/pack
81174 Cryotop®US (B) Blue Closed, Flat Sheet 10/pack
81175 Cryotop®US (Y) Yellow Closed, Flat Sheet 10/pack

Order Number Code Color Specifications Quantity
81195 Cryotop®SUS (G) Green Thicker rounded tip 10/pack
81196 Cryotop®SUS (R) Red Thicker rounded tip 10/pack
81197 Cryotop®SUS (W) White Thicker rounded tip 10/pack
81198 Cryotop®SUS (B) Blue Thicker rounded tip 10/pack
81199 Cryotop®SUS (Y) Yellow Thicker rounded tip 10/pack

Order Number Code Color Specifications Quantity
81131 Cryotop®CL (G) Green Closed 10/pack
81132 Cryotop®CL (R) Red Closed 10/pack
81133 Cryotop®CL (W) White Closed 10/pack
81134 Cryotop®CL (B) Blue Closed 10/pack
81135 Cryotop®CL (Y) Yellow Closed 10/pack

Please note that products may only be available in selected countries.

Vitrification Product Catalog

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Vitrification Protocol

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CryoTop® IFU

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CryoTop®SC IFU

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CryoTop® US/Scoop IFU

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